About Dr. Mori

Dr. Mori is a leading researcher in the field of Protein Quality Control, focusing on the biological and physiological importance of the Unfolded Protein Response.


Blog

カーソルを当てたときに左下に虫眼鏡がでてくる写真はクリックすると拡大します

Go to blog »

Key publications

  • ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish
    Mol. Biol. Cell, 2013
  • Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress
    Mol. Biol. Cell, 2010
  • ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum
    Cell Struc. Func., 2008
  • Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1
    Dev. Cell, 2007
  • A time-dependent phase shift in the mammalian unfolded protein response
    Dev. Cell, 2003
  • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
    Cell, 2001
  • Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
    Mol. Biol. Cell, 1999
  • Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins; involvement of basic leucine zipper transcription factors
    J. Biol. Chem., 1998
  • Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response
    Mol. Biol. Cell, 1997
  • A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
    Cell, 1993
See more »